Innovative programs in healthcare are those that have identified needs in a community and have found creative solutions to meet those needs. This issue of Pediatric Annals highlights five such programs: one program that addresses the needs of children with asthma, another that helps obese children and those at risk for obesity adopt a better diet and lifestyle, a third that educates parents about injury prevention, a fourth that helps identify patients who may need mental health services, and a fifth that reaches out to underserved young people.