Vaccine-Preventable Diseases

Omnibus autism decision: ‘Good science wins out in the end’


Every year, Infectious Diseases in Children’s editorial board votes on the top stories of the previous year, and this year, the Omnibus Autism decision topped the list.

Paul Offit, MD, Chief of Infectious Diseases at Children’s Hospital of Philadelphia and a member of the editorial board, provided an overview of these proceedings at the 22nd Annual Infectious Diseases in Children Symposium in New York this weekend.

Paul Offit, MD
Paul Offit
Photo by Michael P. Hall

On Feb. 12, 2009, a court of special masters ruled that the combination of measles-mumps-rubella and thimerosol-containing vaccine does not cause autism. The ruling involved three test families who have children with autism. The families contended their children’s autism was triggered by a combination of the measles, mumps, rubella vaccines and the preservative thimerosal and were seeking to be compensated through the Vaccine Injury Compensation Program.

About 5,000 families have filed lawsuits based on three areas: those who believe the combination of the MMR vaccine and other thimerosal-containing vaccines causes autism; those who believe MMR vaccines alone cause autism; and those who believe thimerosal-containing vaccines alone cause autism

In his presentation, Offit noted that Andrew Wakefield, the physician who sparked the initial scare over the safety of the MMR vaccine for children, misreported results in his research, creating the appearance of a possible link with autism, which led to many of these lawsuits. Several studies involving thousands of children have since refuted this link.

Offit said he believes that a recommendation to remove thimerosol from vaccines, despite limited evidence linking it to autism, galvanized beliefs in that connection. Several studies that Offit mentioned, however, refuted this link.

Offit said the ruling of the special masters in February “came out on the side of science.”

“Science matters. I really do think that it is worth doing studies because good science wins out in the end,” Offit said. “When you have the science to back it up, you can better communicate with the press and to the public.”

For a complete listing of the editorial board’s picks for stories of the year, see the December issue.by Colleen Zacharyczuk

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Infectious Diseases in Children Symposium

Medical Education Pediatric Annals, February 2010Upper Respiratory Tract Infections Pediatric Annals, January 2010Focus on Influenza Pediatric Annals, December 2009
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